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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd2177b64ca579d60ac081823a743013cad57250936d4114b8cb0ad2c271bf81' 
  AND token = 'E2VYGfvax78RGbbcOJIopKSyqD6q0wN/x28Q2K2CtBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}