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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0e2673c2d107b3e7d3cccc464473a25542decec4dd2253196e07008f8a2692' 
  AND token = 'm85GUIRPwdIhfjOtQOywLMNCAnnxcTAyWST3+qlRq6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}