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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e834311fd10b2be17f6cf28464d8e150fedf61e0bf0727480c8b4bbddb0fabf' 
  AND token = 'BCWEs1wdJQNuayPucEWGYxy/4RsWJVRzFxefLosbP+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}