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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d075588eb70a10b8e902f9fb1b293814d81af367bfd009aa9e5e1ff6177d196' 
  AND token = 'dxt5N+dlIEjdb3C0FW6xVXjeUFPhkFNqkY1neuu2Fs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}