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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8908aebd756d61e602cd992a357a8579828f5f472d18a70b2e41d39c99b5195' 
  AND token = 'yaW9M7JvC0+PSFb2sb3n+BKueUBs+w/c3Dr2aqUKGAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}