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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e4885fe86d51168ac1f0ef36a5cf230e5cb56dc90728f74ce2ad0d5649821e' 
  AND token = 'kqpEdFtiVFjeqmwOQmd0VlDVHTNBTcPnhR/cAjlQRYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}