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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb23c10053cce0522b89c007be923a4a75a7d79ad4eb30053d44c9abda222fa' 
  AND token = '/domEwTc4B+qfZRLguR17kHMw22sVI1G5yDl/j1dSWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}