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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e40f6e52b49500489350074b3591b61f202b17051aec7101b4ab3b9f37ed245' 
  AND token = '2wnZ+CIi+DxJvXs4emdO0XxiGwlAo+S3WnbEqvGuHHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}