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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ad21834436aa5facf96e150ce2d636f65fe52ae666e14906c05f2a03f75bf9' 
  AND token = 'nyRg72IR7g+wbhQbvufB1Sufwan4RHKCGkop1pZKIa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}