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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b725a1ffb7026b81d358407d8aa677c2a6bf385ba18e7e5261b56c9f414686' 
  AND token = 'KKwzXn5GI+U2PRkNuT3cNRFnFoj4kaoGeZvBQLF8fQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}