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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b57e222306f016d6d7d1ad661b1df9fd367ec8b7e223e0ddf211bb7449d8bee' 
  AND token = 'ITJqLRr53lI//tzzsvkaiRffk6nZZOmGYiCTyjoa8xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}