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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4e8a822757e2f63bd81dcefa2c9b54918896a6812f571c640b7c838bf82580' 
  AND token = 'ocOwTpReAFjmK7jB2DzK1WW+krmTOoknt0Ort8Zz3XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}