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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6a3f44c8c8b3f85bb28288b1d248f49bbc3fa890e285886ecdef2a04afb398' 
  AND token = 'VoPfounSTRAZkpdpYAFBDMWMSxHtc5iaLq6V3O6NnMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}