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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a179f575115600f5dc6e848b1e4a1a2960d5f783c87a52ea64fef8c50ee81d' 
  AND token = 'w2a1TdpUAoW+2nbCzEiWaBSkCEoodwf5A+1B/tat/iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}