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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e2ddf3e07c09ae5b31c9f88c4cc28fda4c1cfa67b2866510d87f2e46692794' 
  AND token = 'XL00a9pMyLn4HJs4nyaQVQ8kPoAW6gKwhRTzMuLhhq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}