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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe1c1dd7c253df9e8e4ae0601cc722fd17c233e4e335adbfaee2c430c1bc6b6' 
  AND token = 'QABfG3t6Fb40Z6RY3kKGUYdGThEYv6Fz2Z18iy6UVJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}