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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8bda98cc608ab7474e67ff9f4bf57431b24cc7f03629e78becd637402b4ab67' 
  AND token = 'VruxOnx7Jm6FRJe+YDha8zBk5VyRqTVs0d+6dKuA5vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}