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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '804ffa5d16c81a5c49cff42f98077294a3921d52cb11ad9ac22c4a15acbe703e' 
  AND token = 'ZzkOSa5q+YnXGNxSA1FnL6M18PmyUgOxAwNVdG6BS8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}