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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c746f6bf8a28517e294b24dd349ff7865e37f447f22840b7e4f34170c32a673' 
  AND token = '8tIYswyL5mxgiGNMbj5CHPWqN4X7S+t4yY+8025kTRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}