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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2b4bfc2d2b5475b103107d220658f52e1b33e9fb5333cb77ee2057777c1b91' 
  AND token = 'yc0o8TvbtEoo4QWlAJOXkZTfVtiN+bAi7wg4/L2lM8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}