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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa3872310414f0fa4ff943303e3ca78c55257ad18e4db42a13bf6cc03365387' 
  AND token = 'sS3t4Vc297s5Ty+BYVtPW6MXfj2fOaC5RjC7xNEW26M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}