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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cbd4b72cce5e12f1153d82e68dcc1adc388d2158932c21ac1b8fb2f04236d2' 
  AND token = 'Ccat5oHxlvo/NxDpYt6PuSOueXgU06tRaNfcGboe278=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}