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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744f5ef559537d409b6cd917f52aca21b8fdaecf1eddbf4d369c1d727c0b2ffd' 
  AND token = 'MpKMN6xiZ1HIHAhazyUh94Kj7PLSw4ihSKm1tjgoTec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}