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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3968ccb42bb1ed159c524e52b7a40e432f541ab2d8d35b10d9d04eb6b378b1e0' 
  AND token = '/qxgDhDIxGcypOeEVkybZOajZrA3Y2QtH6oGo+j49q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}