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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6da54b4bf30b88e1425ea86c40b0a4d9df879f6186d67778b5095832da9db4cc' 
  AND token = 'So6dWXXVn7Cah4t25yvCpy538r7/qiKEX0EAy6yOf7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}