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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081ee79ef2675d4f9b0a01061ca7917a194643e17e413b8e7b111d9087687978' 
  AND token = 'A/2GAKZvejT45OgfZmhWWmGz/coxst2po6dfPOgsEnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}