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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6000b54b8c20fbc8a0f943a28d8dce6e24c998f6cd484e0850d64fc5700d5f54' 
  AND token = 'kf0Ge6fzkfnr8QTJtEAaqwSVcV1MhMWBVFRhkPAWhbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}