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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143b1b73fdd54ec7329679c6fabdeb46cfed22364b251084ec79fced180db33b' 
  AND token = 'IRCFo6qwpPwX5Gt82Is0MSNEGVz+J59vEgno+qMX2SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}