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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da80a5007e040af8fb22bf989b6a3b69e422e2336caa277787e3ee22c15e305c' 
  AND token = 'YcYpOraaBYfH6IhHNsPdx8Bh0fiNoDgQvQk/+kr3vdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}