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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7c60cc225a3962d730c20a51943a52488e743564576418b580b528951771e3' 
  AND token = '1iTFmgb9HTrjeXSOCYFOfVbi/9N3TFOzQxQap3A5Acc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}