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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5b3750055167aec57977d1d669d1b779770855a0f9fc7e5c1006a359a56755' 
  AND token = '2RWTavtVctLYSLZ/OTXivuKkd3zWc5kJ2O29Wan56xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}