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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726306ea79d5bd14f42391f288a26f014ac1023dad616e5df4dd91bcbb78e508' 
  AND token = 'hdv8gnZmCLZHWM3OYbrHd6MRjr9kNV/+oY77VayqkCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}