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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a216a358c728496239e77ad7700a049f9f22d8ca8b923091e925675e1aa9fb2c' 
  AND token = 'fCSqnJQnKlmcYh0+zb1DcvBC8+JqGA3y9bkNe3ZHmuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}