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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ed1c43b8b2520c9b635311268e2556bce1bd3b75b2ad36b7ea5901db49b0e4' 
  AND token = 'nBLfmrqe6F/NVPvq/8SP79VhBNYQR4NoME9b4FQO3Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}