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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77014537bf3754e1fb90fa6bee1d7e5508ef3ec3d3b4712d184529045d1d821c' 
  AND token = 'LwKJRPMit27GuGWw7tPOvnsInFRcHWfPXwLDfGskwuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}