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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a12f43a1b821948401fc323644cb38254197fd624b130a3998d429b8958340' 
  AND token = 'sPENQGLIKey+Fy83F5F5gR7/j5bNWUdKE/dpKvabdEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}