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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249d24d5d4acfcbd77aa3a6976dc1d8560719990690e59906a75fa89380ee0ca' 
  AND token = '4UBYNtVJlBWq2Slo1OOnCQaqBVfqfWht3pj9/NwfLsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}