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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52eb889ec840f771cd44461a7c73c26085cc7bb50ea94569b20fdb0b2550192' 
  AND token = 'fGphFdDaCJzOFXTcBjRCw0FsTkaL6/u9WkRtyltBY1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}