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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ea15f896585e3cf098da6cd72d0904422a66f3f6c2315de8ac455b46572930' 
  AND token = 'I9yCLka/4N3k0aGFVGrczy4lUnw4WMzJNOtDTz4Ea3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}