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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486c3a415d46676b69439d6893732b89af21c9a4aa1635a20325f240def1f9fb' 
  AND token = 'XeuSZbLZkCddryLNeoG8cQvz7occ/Uvr33eBfAZ8pG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}