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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bef58e04717b816cb5ff93a8bcb1daf4a3c498ba3e793dd6f5ea8cdd0018489' 
  AND token = '68VJreYsjF1PT3G/fYPWcq0uTot4kUUgiu8rxg3AxKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}