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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06db8f44b750951611582afb1ad16f4b05fdcbb3481dae4c6f8b0c8b3cbdc9d1' 
  AND token = 'x6F25DzjAV/kB1Nq6qCCdvhiXjfEL0eVgdKhyV+bg18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}