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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c038d053f355d671b9d0bbec7540be31bc74eeadc0759cd016b1b52f8f3874' 
  AND token = 'WVJLagboDobid4ij0BKQULG1M0h2vEk5VKJDs717XFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}