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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd67252df897688d2de47ebcf794434c729a694b3d807642f5dd9880f667b449f' 
  AND token = 'UJt+3l7Vq5W7GGD7W8Y3svhJqgMBVItdf5vpuczN7dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}