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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4420a4498f3c0093ed5970b0a7e465ceb13ecc201806a2e144a9b00b5e53d37' 
  AND token = 'EaG1eunHTCiwkMIQXFeXjN+biqlslrDESu2b67s0bA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}