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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a11c8c2c59fa2a3a83ad467578fa516cb91eebf708ed87f5357d33c88e29c42' 
  AND token = 'zToxayYUeKeGpd9dVJ5VStV+bdU8L8DB6VIej7btH/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}