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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86cf93c14f634dbe1658ebf23450a2b71a677985bed8e6cb62e7c3f4967ae3b3' 
  AND token = 'QuMw0dw9xrBRxcZoKoLurdW/6kjAjphnkHuI0MGOL9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}