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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d85de68c91ca3cb06f458de63a05cb75bf5f2840f8398f4fdc84a66cc46718' 
  AND token = 'v+1wxb6679Juy6sQ3gRsIAnWqZ6X+JS6XiZFjDvPvR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}