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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac66001aa4ea2c81b3dc42f0ac02794dcc79e5c7d181bdbe56afaaafb76e104c' 
  AND token = '3ShGamHHi88mstj7bQ/LjXNu2RDTcIOERC1MwQTmfhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}