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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe81ca18a8cd0a9af620e63857a13920f2cd2fb48d21191acb3fb09d7b18374' 
  AND token = 'FgJ7LdRHjvriWNZs0j5XqtME/uTk0YQI8XHQPm6DqAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}